The 39-year-old Venezuelan posted a retirement message on Instagram on Tuesday after going unsigned the first six weeks of the season.
Sánchez went 116-119 with a 4.06 ERA in 364 appearances, 341 as a starter. He spent his first seven years with Miami, going 44-45, then had a 46-49 record in six seasons with Detroit.
On April 26, 2013, Sánchez blanked Atlanta 10-0 and broke the team’s strikeout record held by Mickey Lolich, who struck out 16 batters on two different occasions in 1969.
Sánchez went eight innings in the win, giving up five hits and a walk on 121 pitches.
Sánchez spent his final three seasons with Washington (19-19), missing 2021 because of a cervical nerve impingement and going nearly two years between victories. He didn’t pitch until July last year, finishing 4-6 with a 4.28 ERA in 14 starts.
The last of Sánchez’s five trips to the postseason ended with a championship. He won the opener of the National League championship series in 2019, allowing one hit in 7 2/3 scoreless innings in Washington’s 2-0 victory over St. Louis.
Sánchez was the losing pitcher in Game 3 of the World Series, but Washington beat Houston in seven games. He also lost Game 3 with Detroit in the 2012 World Series, which San Francisco swept.
“During my career, I have met people who, like me, fought tirelessly to reach the big leagues, my teammates,” Sánchez wrote. “It is true that we are from different cultures and speak different languages, and it is in the humility of wanting to learn from each other where we become a team.”